PSQ01051
FD00328
Oncostatin-M
P13725
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
31
cytokine activity, growth factor activity, oncostatin-M receptor binding
252
None
OSM
9606
extracellular region, extracellular space
cytokine-mediated signaling pathway, immune response, multicellular organism development, negative regulation of cell population proliferation, negative regulation of hormone secretion, oncostatin-M-mediated signaling pathway, positive regulation of acute inflammatory response, positive regulation of cell division, positive regulation of cell population proliferation, positive regulation of inflammatory response, positive regulation of interleukin-17 production, positive regulation of MAPK cascade, positive regulation of peptidyl-serine phosphorylation, positive regulation of peptidyl-tyrosine phosphorylation, positive regulation of phosphatidylinositol 3-kinase signaling, positive regulation of protein kinase B signaling, positive regulation of transcription by RNA polymerase II, positive regulation of tyrosine phosphorylation of STAT protein, regulation of growth, regulation of hematopoietic stem cell differentiation
2325640
31
222:252
HSPHQALRKGVRRTRPSRKGKRLMTRGQLPR
PSQ01052
FD00148
Bone marrow proteoglycan
P13727
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
89
carbohydrate binding, extracellular matrix structural constituent conferring compression resistance, heparin binding
222
Proteoglycan 2
PRG2
9606
collagen-containing extracellular matrix, extracellular exosome, extracellular region, ficolin-1-rich granule lumen, transport vesicle
defense response to bacterium, neutrophil degranulation
2501794, 3410852
89
17:105
LHLRSETSTFETPLGAKTLPEDEETPEQEMEETPCRELEEEEEWGSGSEDASKKDGAVESISVPDMVDKNLTCPEEEDTVKVVGIPGCQ
PSQ01053
FD00590
Endoglucanase 1
P13933
Bacteria Actinobacteria Streptomycetales Streptomycetaceae Streptomyces
Streptomyces sp
200
cellulase activity
360
CMCase I, Carboxymethyl cellulase, Cellulase, Endo-1
casA
74575
None
cellulose catabolic process
3410319
200
70:269
AGTTALPSMELYRAEAGVHAWLDANPGDHRAPLIAERIGSQPQAVWFAGAYNPGTITQQVAEVTSAAAAAGQLPVVVPYMIPFRDCGNHSGGGAPSFAAYAEWSGLFAAGLGSEPVVVVLEPDAIPLIDCLDNQQRAERLAALAGLAEAVTDANPEARVYYDVGHSAWHAPAAIAPTLVEAGILEHGAGIATNISNYRTT
PSQ01054
FD00547
CD59 glycoprotein
P13987
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
26
complement binding
128
1F5 antigen, 20 kDa homologous restriction factor, MAC-inhibitory protein, MEM43 antigen, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, Protectin
CD59
9606
anchored component of external side of plasma membrane, cell surface, endoplasmic reticulum membrane, endoplasmic reticulum-Golgi intermediate compartment membrane, ER to Golgi transport vesicle membrane, extracellular exosome, extracellular space, focal adhesion, Golgi membrane, membrane, plasma membrane, specific granule membrane, tertiary granule membrane, transport vesicle, vesicle
blood coagulation, cell surface receptor signaling pathway, COPII vesicle coating, endoplasmic reticulum to Golgi vesicle-mediated transport, negative regulation of activation of membrane attack complex, neutrophil degranulation, regulation of complement activation, regulation of complement-dependent cytotoxicity
9054419
26
103:128
GGTSLSEKTVLLLVTPFLAAAWSLHP
PSQ01055
FD00012
Chymopapain
P14080
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Caricaceae Carica
Carica papaya (Papaya)
116
cysteine-type peptidase activity
359
Papaya proteinase II
None
3649
None
None
2106878, 2500950
116
19:134
IHMGLSSADFYTVGYSQDDLTSIERLIQLFDSWMLKHNKIYESIDEKIYRFEIFRDNLMYIDETNKKNNSYWLGLNGFADLSNDEFKKKYVGFVAEDFTGLEHFDNEDFTYKHVTN
PSQ01056
FD00204
Cathepsin E
P14091
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
34
aspartic-type endopeptidase activity, identical protein binding, peptidase activity
396
None
CTSE
9606
endosome
antigen processing and presentation of exogenous peptide antigen via MHC class II, protein autoprocessing, proteolysis
2334440, 8346912
34
20:53
SLHRVPLRRHPSLKKKLRARSQLSEFWKSHNLDM
PSQ01057
FD00434
Endoglucanase 3
P14250
Bacteria Fibrobacteres Fibrobacterales Fibrobacteraceae Fibrobacter
Fibrobacter succinogenes (strain ATCC 19169
242
cellulase activity
660
Cellulase 3, Endo-1
cel-3
59374
membrane
cellulose catabolic process
2676979
242
24:265
CGDENTQALFANNPVPGAENQVPVSSSDMSPTSSDAVIDPTSSSAAVVDPSTLPAEGPITMPEGLGTLVDDFEDGDNLSKIGDYWYTYNDNDNGGASIITTPLNEEENIIPGRVNNGSNYALQVNYTLDRGDYEYDPYVGWGVQVAPDEANGHFGGLTYWYKGGAHEVHIEITDVEDYDVHLAKFPASRTWKQAVVRFKDLVQGGWGKEIPFDAKHIMAISFQAKGNKSKLVTDSLFIDNIY
PSQ01058
FD00163
Pectinesterase 1
P14280
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Solanoideae Solaneae Solanum Solanum subgen Lycopersicon
Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
190
aspartyl esterase activity, pectinesterase activity, pectinesterase inhibitor activity
546
Pectin methylesterase 1
PME1
4081
cell wall, extracellular region
cell wall modification, fruit ripening, pectin catabolic process
3732279
190
40:229
YQVEIKHSNLCKTAQDSQLCLSYVSDLISNEIVTTESDGHSILMKFLVNYVHQMNNAIPVVRKMKNQINDIRQHGALTDCLELLDQSVDFASDSIAAIDKRSRSEHANAQSWLSGVLTNHVTCLDELDSFTKAMINGTNLEELISRAKVALAMLASLTTQDEDVFMTVLGKMPSWVSSMDRKLMESSGKD
PSQ01059
FND00282
Delta-hormotoxin-Cpt1b
P14531
Eukaryota Metazoa Cnidaria Anthozoa Hexacorallia Actiniaria Nynantheae Hormathiidae Calliactis
Calliactis parasitica (Sea anemone) (Actinia parasitica)
11
toxin activity
79
Calitoxin , Calitoxin-1 , Neurotoxic peptide
None
6114
extracellular region, nematocyst
None
2567180
11
21:31
RTTLNKRNDIE
PSQ01060
FD00401
Fibronectin-binding protein A
P14738
Bacteria Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus
Staphylococcus aureus (strain NCTC 8325
33
fibrinogen binding, fibronectin binding
1020
None
fnbA
93061
cell wall, extracellular region
aggregation of unicellular organisms, cell adhesion, pathogenesis
11830639, 14769030
33
986:1018
GGEESTNKGMLFGGLFSILGLALLRRNKKNHKA
PSQ01061
FD00040
Elastase
P14756
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas
Pseudomonas aeruginosa (strain ATCC 15692 , 14847
174
endopeptidase activity, metal ion binding, metalloendopeptidase activity
498
Neutral metalloproteinase, PAE , Pseudolysin
lasB
208964
extracellular region
bacterial-type flagellum-dependent swarming motility, pathogenesis, protein secretion by the type II secretion system, protein transport by the Sec complex, proteolysis, single-species biofilm formation
1544509, 2123831, 3034864, 9642203
174
24:197
ADLIDVSKLPSKAAQGAPGPVTLQAAVGAGGADELKAIRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVANIAADLPGSTTAAVSAEQVLAQAKSLKAQGRKTENDKVELVIRLGENNIAQLVYNVSYLIPGEGLSRPHFVIDAKTGEVLDQWEGLAH
PSQ01062
FD00563
Protease LasA
P14789
Bacteria Proteobacteria Gammaproteobacteria Pseudomonadales Pseudomonadaceae Pseudomonas
Pseudomonas aeruginosa (strain ATCC 15692 , 14847
205
endopeptidase activity, metal ion binding, metalloendopeptidase activity
420
Staphylolytic protease
lasA
208964
extracellular space
pathogenesis, peptidoglycan catabolic process, protein secretion by the type II secretion system, protein transport by the Sec complex, proteolysis, septum digestion after cytokinesis
2110137, 9642203
205
32:236
HDDGLPAFRYSAELLGQLQLPSVALPLNDDLFLYGRDAEAFDLEAYLALNAPALRDKSEYLEHWSGYYSINPKVLLTLMVMQSGPLGAPDERALAAPLGRLSAKRGFDAQVRDVLQQLSRRYYGFEEYQLRQAAARKAVGEDGLNAASAALLGLLREGAKVSAVQGGNPLGAYAQTFQRLFGTPAAELLQPSNRVARQLQAKAAL
PSQ01063
FD00045
Concanavalin-A
P14894
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade indigoferoid/millettioid clade Phaseoleae Canavalia
Canavalia gladiata (Sword bean) (Dolichos gladiatus)
15
mannose binding, metal ion binding, monosaccharide binding
290
None
None
3824
None
negative regulation of transcription, DNA-templated, positive regulation of cell division, positive regulation of mitotic nuclear division, regulation of defense response to virus
15935326
15
149:163
VIRNSTTIDFNAAYN
PSQ01064
FD00205
Mast cell carboxypeptidase A
P15088
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
94
metallocarboxypeptidase activity, zinc ion binding
420
Carboxypeptidase A3
CPA3
9606
collagen-containing extracellular matrix, extracellular region, extracellular space, secretory granule, transport vesicle
angiotensin maturation, proteolysis
2708524
94
16:109
IAPVRFDREKVFRVKPQDEKQADIIKDLAKTNELDFWYPGATHHVAANMMVDFRVSEKESQAIQSALDQNKMHYEILIHDLQEEIEKQFDVKED
PSQ01065
FD00319
LIRP
P15131
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Polyneoptera Orthoptera Caelifera Acrididea Acridomorpha Acridoidea Acrididae Oedipodinae Locusta
Locusta migratoria (Migratory locust)
14, 6
hormone activity
145
Locusta insulin-related peptide
None
7004
extracellular region
None
1935945;1935945
20
20:33, 117:122
TQAQSDLFLLSPKR, FRRRTR
PSQ01066
FD00058
Snake venom metalloproteinase atrolysin-D
P15167
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Crotalus
Crotalus atrox (Western diamondback rattlesnake)
170
metal ion binding, metalloendopeptidase activity, toxin activity
420
Hemorrhagic metalloproteinase atrolysin D, Hemorrhagic toxin D
None
8730
extracellular region
collagen catabolic process
2745407
170
21:190
IILESGNVNDYEVVYPRKVTALPKGAVQPKYEDAMQYELKVNGEPVVLHLEKNKELFSKDYSETHYSPDGRKITTNPSVEDHCYYRGRIENDADSTASISACNGLKGHFKLQGEMYLIEPLELSDSEAHAVFKLENVEKEDEAPKMCGVTQNWESYEPIKKASDLNLNPD
PSQ01067
FD00333
PIII-type proteinase
P15292
Bacteria Firmicutes Bacilli Lactobacillales Streptococcaceae Lactococcus
Lactococcus lactis subsp
154
serine-type endopeptidase activity
1962
Cell wall-associated serine proteinase, Lactocepin
prtP
272622
cell wall, extracellular region, membrane
None
2760036
154
34:187
AISQQTKGSSLANTVTAATAKQAATDTTAATTNQAIATQLAAKGIDYNKLNKVQQQDIYVDVIVQMSAAPASENGTLRTDYSSTAEIQQETNKVIAAQASVKAAVEQVTQQTAGESYGYVVNGFSTKVRVVDIPKLKQIAGVKTVTLAKVYYPT
PSQ01068
FD00436
Allergen Sin a 1
P15322
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Brassiceae Sinapis
Sinapis alba (White mustard) (Brassica hirta)
15
nutrient reservoir activity
145
Allergen Sin a I
None
3728
None
None
3181153
15
40:54
WTLDDEFDFEDDMEN
PSQ01069
FD00305
Scytalidopepsin B
P15369
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Leotiomycetes Leotiomycetes incertae sedis Scytalidium
Scytalidium lignicola (Hyphomycete)
34
aspartic-type endopeptidase activity
260
Acid protease B
None
5539
None
None
6370989
34
21:54
APGGNGFARRQARRQARAAGLKASPFRQVNAKEA
PSQ01070
FD00028
2S seed storage protein 1
P15457
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
16, 10
nutrient reservoir activity
164
2S albumin storage protein, NWMU2-2S albumin 1
AT2S1
3702
None
None
16666238;16666238
26
22:37, 74:83
SIYRTVVEFEEDDATN, EFDFEDDMEN
PSQ01071
FD00006
Alpha-conotoxin SI
P15471
Eukaryota Metazoa Spiralia Lophotrochozoa Mollusca Gastropoda Caenogastropoda Neogastropoda Conoidea Conidae Conus Pionoconus
Conus striatus (Striated cone)
28
acetylcholine receptor inhibitor activity, toxin activity
64
None
None
6493
extracellular region, host cell postsynaptic membrane
pathogenesis
3196703
28
22:49
FPSDRASDGRDDEAKDERSDMHESDRKE
PSQ01072
FD00112
Globulin-1 S allele
P15590
Eukaryota Viridiplantae Streptophyta Embryophyta Tracheophyta Spermatophyta Magnoliopsida Liliopsida Poales Poaceae PACMAD clade Panicoideae Andropogonodae Andropogoneae Tripsacinae Zea
Zea mays (Maize)
68
nutrient reservoir activity
573
7S-like
GLB1
4577
None
None
2775172
68
19:86
AVASSWEDDNHHHHGGHKSGRCVRRCEDRPWHQRPRCLEQCREEEREKRQERSRHEADDRSGEGSSED
PSQ01073
FD00505
Protease 1
P15636
Bacteria Proteobacteria Betaproteobacteria Burkholderiales Alcaligenaceae Achromobacter
Achromobacter lyticus
185
serine-type endopeptidase activity
660
API, Lysyl endopeptidase, Protease I
None
224
extracellular region
None
2492988
185
21:205
APASRPAAFDYANLSSVDKVALRTMPAVDVAKAKAEDLQRDKRGDIPRFALAIDVDMTPQNSGAWEYTADGQFAVWRQRVRSEKALSLNFGFTDYYMPAGGRLLVYPATQAPAGDRGLISQYDASNNNSARQLWTAVVPGAEAVIEAVIPRDKVGEFKLRLTKVNHDYVGFGPLARRLAAASGEK
PSQ01074
FD00360
Photosystem II reaction center protein K
P15819
Bacteria Cyanobacteria Synechococcales Merismopediaceae Synechocystis unclassified Synechocystis
Synechocystis sp
8
None
45
None
psbK
1111708
integral component of membrane, photosystem II reaction center, plasma membrane-derived thylakoid membrane, plasma membrane-derived thylakoid photosystem II
photosynthesis
12069591, 1904061
8
1:8
METIYLLA
PSQ01075
FD00007
Kallikrein-1
P15947
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
6
endopeptidase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, serine-type endopeptidase activity
261
Glandular kallikrein K1, KAL-B, Renal kallikrein, Tissue kallikrein-6
Klk1
10090
extracellular space, protein-containing complex, secretory granule
regulation of systemic arterial blood pressure, zymogen activation
1639762
6
19:24
PPVQSR
PSQ01076
FD00007
Kallikrein 1-related peptidase b22
P15948
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Mus Mus
Mus musculus (Mouse)
7
endopeptidase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides, peptidase activity, serine-type endopeptidase activity
259
Beta-NGF-endopeptidase, Epidermal growth factor-binding protein type A, Glandular kallikrein K22, Nerve growth factor beta chain endopeptidase, Tissue kallikrein 22
Klk1b22
10090
extracellular space, protein-containing complex, secretory granule
regulation of systemic arterial blood pressure, zymogen activation
1639762, 2012805
7
18:24
APPVQSR
PSQ01077
FND00261
Omega-agatoxin-1A
P15969
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Agelenidae Agelenopsis
Agelenopsis aperta (North American funnel-web spider) (Agelenopsis, gertschi)
17
toxin activity
119
Omega-agatoxin IA
None
6908
extracellular region
pathogenesis
2295621
17
20:36
VEGEEEYFEAEVPELER
PSQ01078
FD00149
Photosystem II protein D1 2
P16033
Bacteria Cyanobacteria Synechococcales Merismopediaceae Synechocystis unclassified Synechocystis
Synechocystis sp
16
chlorophyll binding, electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity, iron ion binding, oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor, oxygen evolving activity
360
Photosystem II Q(B) protein 2
psbA2 , psbA3
1111708
integral component of membrane, photosystem II, plasma membrane-derived thylakoid membrane, plasma membrane-derived thylakoid photosystem II
photosynthetic electron transport in photosystem II, protein-chromophore linkage, response to herbicide
8034700
16
345:360
SGEQAPVALTAPAVNG
PSQ01079
FD00004
Trypsin-1
P16049
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Neoteleostei Acanthomorphata Zeiogadaria Gadariae Gadiformes Gadoidei Gadidae Gadus
Gadus morhua (Atlantic cod)
6
serine-type endopeptidase activity
241
Trypsin I
None
8049
extracellular space
digestion
2707266
6
14:19
FAEEDK
PSQ01080
FD00184
Sodium/potassium ATPase inhibitor SPAI-2
P16225
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Suina Suidae Sus
Sus scrofa (Pig)
105
serine-type endopeptidase inhibitor activity
187
Protein WAP-2
None
9823
extracellular space
antibacterial humoral response, copulation, innate immune response
2553020
105
22:126
QRLDRIRGPKGQGQDPVEGQDQDEGPGPVKVEILDIGQDPVKGQDPVKGQDPVKGQDPVKGQDLVKSQDPVKAELPDIGQDVVKGHEPVEGQDPVNAQLPDKVQD
PSQ01081
FD00043
Cathepsin E
P16228
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
37
aspartic-type endopeptidase activity, identical protein binding, peptidase activity
398
None
Ctse
10116
endosome
antigen processing and presentation of exogenous peptide antigen via MHC class II, protein autoprocessing, proteolysis
2105725
37
22:58
VLHRVPLRRHQSLRKKLRAQGQLSDFWRSHNLDMIEF
PSQ01082
FD00061
Cionin
P16240
Eukaryota Metazoa Chordata Tunicata Ascidiacea Phlebobranchia Cionidae Ciona
Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis)
86
hormone activity
128
None
None
7719
extracellular region
neuropeptide signaling pathway
2303439
86
23:108
PASDLFKSVSQYHIPRSKVINKETVTKPLQFQRAICRLLQKLGEETFARLSQSELEAKQLDLIKTCYQANSFGDNENQGHMQRMDR
PSQ01083
FD00078
Peptidase 1
P16311
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Psoroptidia Analgoidea Pyroglyphidae Dermatophagoidinae Dermatophagoides
Dermatophagoides farinae (American house dust mite)
80
cysteine-type peptidase activity
321
Allergen Der f I, Major mite fecal allergen Der f 1
DERF1
6954
extracellular region
None
3372999
80
19:98
RPASIKTFEEFKKAFNKNYATVEEEEVARKNFLESLKYVEANKGAINHLSDLSLDEFKNRYLMSAEAFEQLKTQFDLNAE
PSQ01084
FD00394
Dipeptidase 1
P16444
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
26
beta-lactamase activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, GPI anchor binding, metallodipeptidase activity, metalloexopeptidase activity, modified amino acid binding, zinc ion binding
418
Beta-lactamase , Dehydropeptidase-I, Microsomal dipeptidase , Renal dipeptidase
DPEP1
9606
anchored component of membrane, apical part of cell, apical plasma membrane, cell junction, extracellular exosome, extracellular space, microvillus membrane, nucleoplasm, plasma membrane
aflatoxin metabolic process, antibiotic metabolic process, cellular lactam catabolic process, cellular response to calcium ion, cellular response to drug, cellular response to nitric oxide, glutathione catabolic process, glutathione metabolic process, homocysteine metabolic process, inflammatory response, leukotriene metabolic process, lipid metabolic process, negative regulation of apoptotic process, negative regulation of cell migration, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, negative regulation of inflammatory response to antigenic stimulus, neutrophil chemotaxis
2168407
26
386:411
GASSLHRHWGLLLASLAPLVLCLSLL
PSQ01085
FD00322
Protein-lysine 6-oxidase
P16636
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Glires Rodentia Myomorpha Muroidea Muridae Murinae Rattus
Rattus norvegicus (Rat)
141
collagen binding, copper ion binding, protein-lysine 6-oxidase activity
418
Lysyl oxidase
Lox
10116
collagen trimer, extracellular matrix, extracellular region, extracellular space, nucleus
aorta development, ascending aorta development, blood vessel development, blood vessel morphogenesis, bone mineralization, cell chemotaxis, cellular response to chemokine, cellular response to organic substance, collagen fibril organization, connective tissue development, descending aorta development, DNA biosynthetic process, elastic fiber assembly, heart development, lung development, muscle cell cellular homeostasis, muscle fiber development, osteoblast differentiation, peptidyl-lysine oxidation, platelet-derived growth factor receptor-beta signaling pathway, protein kinase B signaling, protein oxidation, regulation of apoptotic process, regulation of bone development, regulation of gene expression, regulation of megakaryocyte differentiation, regulation of platelet-derived growth factor receptor-beta signaling pathway, regulation of protein phosphorylation, regulation of receptor binding, regulation of striated muscle tissue development, regulation of transforming growth factor beta receptor signaling pathway, response to drug, response to hormone, response to steroid hormone, wound healing
8636146
141
22:162
APQAPREPPAAPGAWRQTIQWENNGQVFSLLSLGAQYQPQRRRDSSATAPRADGNAAAQPRTPILLLRDNRTASARARTPSPSGVAAGRPRPAARHWFQVGFSPSGAGDGASRRAANRTASPQPPQLSNLRPPSHVDRMVG
PSQ01086
FD00340
Uteroferrin-associated protein
P16708
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Suina Suidae Sus
Sus scrofa (Pig)
15
serine-type endopeptidase inhibitor activity
420
None
None
9823
extracellular space
female pregnancy, negative regulation of endopeptidase activity
2342477
15
26:40
EKQQTSPKTITPVSF
PSQ01087
FD00263
Major core protein 4a precursor
P16715
Viruses Varidnaviria Bamfordvirae Nucleocytoviricota Pokkesviricetes Chitovirales Poxviridae Chordopoxvirinae Orthopoxvirus Vaccinia virus
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain, WR))
83
structural molecule activity
898
Virion core protein 4a precursor
None
10254
virion
None
1853556
83
615:697
SPEGEETIICDSEPISILDRIDTRGIFSAYTINEMMDTDIFSPENKAFKNNLSRFIESGDITGEDIFCAMPYNILDRIITNAG
PSQ01088
FND00242
KP6 killer toxin
P16948
Viruses Riboviria Orthornavirae Duplornaviricota Chrymotiviricetes Ghabrivirales Totiviridae Totivirus
Ustilago maydis P6 virus (UmV6) (UmV-P6)
8, 33
toxin activity
219
Killer protein 6
None
11010
extracellular region
None
2181272;2181272
41
20:27, 106:138
LPNGLSPR, KRTIQDSATDTVDLGAELHRDDPPPTASDIGKR
PSQ01089
FD00353
Thermopsin
P17118
Archaea Crenarchaeota Thermoprotei Sulfolobales Sulfolobaceae Sulfolobus
Sulfolobus acidocaldarius (strain ATCC 33909 , 15157
13
aspartic-type endopeptidase activity
340
None
thpS
330779
extracellular region
None
2104843
13
29:41
HRNTTGATISSGL
PSQ01090
FD00015
Zinc metalloproteinase
P17349
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Lepidosauria Squamata Bifurcata Unidentata Episquamata Toxicofera Serpentes Colubroidea Viperidae Crotalinae Protobothrops
Protobothrops elegans (Elegant pitviper) (Trimeresurus elegans)
16
metal ion binding, metalloendopeptidase activity, toxin activity
481
None
None
88086
extracellular region
None
2191722, 8920980
16
393:408
LRTDTVSTPVSGNEFL
PSQ01091
FD00031
Defensin-1
P17722
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Hymenoptera Apocrita Aculeata Apoidea Apidae Apis
Apis mellifera (Honeybee)
24
None
95
Royalisin
None
7460
extracellular region
defense response to bacterium, innate immune response
2358464
24
20:43
APVEDEFEPLEHFENEERADRHRR
PSQ01092
FD00231
Mu-ctenitoxin-Pn1a
P17727
Eukaryota Metazoa Ecdysozoa Arthropoda Chelicerata Arachnida Araneae Araneomorphae Entelegynae Lycosoidea Ctenidae Phoneutria
Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer)
14
toxin activity
119
Toxin Tx1
None
6918
extracellular region
pathogenesis
16278100, 16505156, 1801316, 2335228
14
20:33
EEMIEGENPLEDQR
PSQ01093
FD00293
SpoIVB peptidase
P17896
Bacteria Firmicutes Bacilli Bacillales Bacillaceae Bacillus
Bacillus subtilis (strain 168)
24
serine-type peptidase activity
426
Sporulation factor IV B protease, Stage IV sporulation protein B
spoIVB
224308
None
sporulation resulting in formation of a cellular spore
10931284
24
29:52
YLLIPTQMRVFETQTQAIETSLSV
PSQ01094
FD00339
Ganglioside GM2 activator
P17900
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
8
beta-N-acetylgalactosaminidase activity, lipid transporter activity, phospholipase activator activity
193
Cerebroside sulfate activator protein, GM2-AP, Sphingolipid activator protein 3
GM2A
9606
apical plasma membrane, azurophil granule lumen, basolateral plasma membrane, cytoplasmic side of plasma membrane, cytosol, extracellular exosome, extracellular region, intracellular membrane-bounded organelle, lysosomal lumen
ganglioside catabolic process, glycosphingolipid metabolic process, learning or memory, lipid storage, lipid transport, neuromuscular process controlling balance, neutrophil degranulation, oligosaccharide catabolic process, positive regulation of hydrolase activity
2209618
8
24:31
HLKKPSQL
PSQ01095
FD00030
Aspergillopepsin-1
P17946
Eukaryota Fungi Dikarya Ascomycota Pezizomycotina Eurotiomycetes Eurotiomycetidae Eurotiales Aspergillaceae Aspergillus
Aspergillus awamori (Black koji mold)
49
aspartic-type endopeptidase activity
394
Aspartic protease pepA, Aspergillopepsin A , Aspergillopepsin I, Aspergillopeptidase A
pepA
105351
extracellular region
None
2182390
49
21:69
APAPTRKGFTINQIARPANKTRTINLPGMYARSLAKFGGTVPQSVKEAA
PSQ01096
FD00535
Bone morphogenetic protein 7
P18075
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo
Homo sapiens (Human)
263
BMP receptor binding, cytokine activity, growth factor activity, heparin binding
431
Osteogenic protein 1
BMP7
9606
collagen-containing extracellular matrix, extracellular region, extracellular space, vesicle
allantois development, axon guidance, BMP signaling pathway, branching involved in salivary gland morphogenesis, branching morphogenesis of an epithelial tube, cardiac muscle tissue development, cardiac septum morphogenesis, cartilage development, cellular response to BMP stimulus, cellular response to hypoxia, chorio-allantoic fusion, dendrite development, embryonic camera-type eye morphogenesis, embryonic limb morphogenesis, embryonic pattern specification, embryonic skeletal joint morphogenesis, endocardial cushion formation, epithelial cell differentiation, epithelial to mesenchymal transition, heart trabecula morphogenesis, hindbrain development, mesenchymal cell differentiation, mesenchyme development, mesoderm formation, mesonephros development, metanephric mesenchymal cell proliferation involved in metanephros development, metanephric mesenchyme morphogenesis, metanephros development, monocyte aggregation, negative regulation of cell cycle, negative regulation of cell death, negative regulation of glomerular mesangial cell proliferation, negative regulation of MAP kinase activity, negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis, negative regulation of mitotic nuclear division, negative regulation of neurogenesis, negative regulation of neuron differentiation, negative regulation of NF-kappaB transcription factor activity, negative regulation of NIK/NF-kappaB signaling, negative regulation of Notch signaling pathway, negative regulation of phosphorylation, negative regulation of prostatic bud formation, negative regulation of striated muscle cell apoptotic process, negative regulation of transcription, DNA-templated, nephrogenic mesenchyme morphogenesis, neural fold elevation formation, neuron projection morphogenesis, odontogenesis of dentin-containing tooth, ossification, pericardium morphogenesis, pharyngeal system development, positive regulation of apoptotic process, positive regulation of bone mineralization, positive regulation of brown fat cell differentiation, positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis, positive regulation of dendrite development, positive regulation of epithelial to mesenchymal transition, positive regulation of gene expression, positive regulation of heterotypic cell-cell adhesion, positive regulation of hyaluranon cable assembly, positive regulation of neuron differentiation, positive regulation of osteoblast differentiation, positive regulation of pathway-restricted SMAD protein phosphorylation, positive regulation of peptidyl-threonine phosphorylation, positive regulation of transcription by RNA polymerase II, positive regulation of transcription, DNA-templated, protein localization to nucleus, regulation of branching involved in prostate gland morphogenesis, regulation of pathway-restricted SMAD protein phosphorylation, regulation of removal of superoxide radicals, response to estradiol, response to peptide hormone, response to vitamin D, skeletal system development, SMAD protein signal transduction, steroid hormone mediated signaling pathway, ureteric bud development
17977014
263
30:292
DFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPRPHLQGKHNSAPMFMLDLYNAMAVEEGGGPGGQGFSYPYKAVFSTQGPPLASLQDSHFLTDADMVMSFVNLVEHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKDYIRERFDNETFRISVYQVLQEHLGRESDLFLLDSRTLWASEEGWLVFDITATSNHWVVNPRHNLGLQLSVETLDGQSINPKLAGLIGRHGPQNKQPFMVAFFKATEVHFRSIR
PSQ01097
FD00037
C-type natriuretic peptide
P18104
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Laurasiatheria Artiodactyla Suina Suidae Sus
Sus scrofa (Pig)
50
hormone activity, hormone receptor binding, signaling receptor binding
126
None
NPPC
9823
extracellular region, protein-containing complex
cGMP biosynthetic process, growth plate cartilage chondrocyte differentiation, growth plate cartilage chondrocyte proliferation, negative regulation of meiotic cell cycle, negative regulation of oocyte maturation, ossification, post-embryonic development, protein folding, receptor guanylyl cyclase signaling pathway, regulation of multicellular organism growth, reproductive process
2383278
50
24:73
KPGAPPKVPRTPPGEEVAEPQAAGGGQKKGDKTPGGGGANLKGDRSRLLR
PSQ01098
FD00037
C-type natriuretic peptide
P18145
Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Actinopterygii Neopterygii Teleostei Anguilliformes Anguillidae Anguilla
Anguilla japonica (Japanese eel)
89
hormone activity
131
BNP-like peptide CNP-22
cnp
7937
extracellular region
cGMP biosynthetic process, receptor guanylyl cyclase signaling pathway
2143379
89
21:109
DSRALRTPVDAIQFVEQFLEHYNDLLNIDDLENQTGDQLESPQPLSSGLKVAEYPKWVDVPSQNDNTWFRLLRGALANRKRALPDRAKR
PSQ01099
FD00072
Photosystem II reaction center protein K
P18263
Eukaryota Viridiplantae Chlorophyta core chlorophytes Chlorophyceae Chlamydomonadales Chlamydomonadaceae Chlamydomonas
Chlamydomonas reinhardtii (Chlamydomonas smithii)
9
None
46
None
psbK
3055
chloroplast thylakoid membrane, integral component of membrane, photosystem II reaction center
photosynthesis
1885590
9
1:9
MTTLALVLA
PSQ01100
FD00031
Sapecin
P18313
Eukaryota Metazoa Ecdysozoa Arthropoda Hexapoda Insecta Pterygota Neoptera Holometabola Diptera Brachycera Muscomorpha Oestroidea Sarcophagidae Sarcophaga Boettcherisca
Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
31
None
94
None
None
7386
extracellular region
defense response to bacterium, innate immune response
3182836
31
24:54
SPAAAAEESKFVDGLHALKTIEPELHGRYKR