Details of family id : FD00481
| Family ID |
FD00481 |
| Protein Name |
Caspase-4 |
| UniProt ID |
P49662
|
| Prosequence Length Range (aa) |
19
|
| Preproprotein Length Range(aa) |
377 |
| Preproprotein pI Range |
5.69 |
| Preproprotein Molecular Weight Range (D) |
43262.25 |
| Prosequence pI Range (D) |
3.45 |
| Prosequence Molecular Weight Range |
1979 |
| Domains |
cd08325 : smart00115 |
| Organisms |
Homo sapiens (Human) |
| Functions |
CARD domain binding; cysteine-type endopeptidase activity; cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
| Cellular Localization |
AIM2 inflammasome complex; cytoplasm; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; extracellular region; IPAF inflammasome complex; mitochondrion; NLRP3 inflammasome complex; plasma membrane; protein-containing complex |
| Processes |
apoptotic process; cellular response to amyloid-beta; execution phase of apoptosis; inflammatory response; innate immune response; intrinsic apoptotic signaling pathway; intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress; positive regulation of tumor necrosis factor-mediated signaling pathway; protein autoprocessing; proteolysis; pyroptosis; regulation of apoptotic process; regulation of inflammatory response |
| Common Name |
Caspase |
