Details of family id : FD00298
| Family ID |
FD00298 |
| Protein Name |
Interleukin-33 |
| UniProt ID |
O95760
|
| Prosequence Length Range (aa) |
94
|
| Preproprotein Length Range(aa) |
270 |
| Preproprotein pI Range |
8.89 |
| Preproprotein Molecular Weight Range (D) |
30759.38 |
| Prosequence pI Range (D) |
10.31 |
| Prosequence Molecular Weight Range |
10951.16 |
| Domains |
pfam15095 |
| Organisms |
Homo sapiens (Human) |
| Functions |
cytokine activity; interleukin-33 receptor binding |
| Cellular Localization |
chromosome; cytoplasm; extracellular region; extracellular space; intracellular membrane-bounded organelle; nucleoplasm; nucleus; transport vesicle |
| Processes |
defense response to virus; extrinsic apoptotic signaling pathway; interleukin-33-mediated signaling pathway; microglial cell activation involved in immune response; microglial cell proliferation; negative regulation of immunoglobulin production; negative regulation of interferon-gamma production; negative regulation of leukocyte migration; negative regulation of macrophage proliferation; negative regulation of T-helper 1 type immune response; negative regulation of transcription by RNA polymerase II; positive regulation of CD80 production; positive regulation of CD86 production; positive regulation of cellular defense response; positive regulation of chemokine production; positive regulation of cytokine production; positive regulation of gene expression; positive regulation of immunoglobulin production; positive regulation of inflammatory response; positive regulation of interleukin-13 production; positive regulation of interleukin-4 production; positive regulation of interleukin-5 production; positive regulation of interleukin-6 production; positive regulation of macrophage activation; positive regulation of MHC class I biosynthetic process; positive regulation of MHC class II biosynthetic process; positive regulation of neuroinflammatory response; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; positive regulation of transcription by RNA polymerase II; positive regulation of tumor necrosis factor production; positive regulation of type 2 immune response; protein deubiquitination |
| Common Name |
Interleukin |
